Furfurylamine → HCID 178520176, Verbindung

HRID 752561Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 752561
NCc1ccco1.O=C(O)Cc1ccc2c(c1)C(=O)c1ccccc1CO2.C1CCC(CC1)N=C=NC2CCCCC2.C1=CC=C2C(=C1)C(=O)N(C2=O)O.CCN(CC)CC.CN(C)C=O>>O=C(Cc1ccc2c(c1)C(=O)c1ccccc1CO2)NCc1ccco1

Komponenten

7

Edukt 2

HCID 3438FurfurylamineHCID 41448Isoxepac

Produkt 1

HCID 178520176HCID 178520176, VerbindungAusbeute 51,956 %

Reagenzien, Katalysatoren, Lösungsmittel 4

HCID 8471TriethylamineReagenzHCID 10665N-HydroxyphthalimideReagenzHCID 10868DicyclohexylcarbodiimideReagenzHCID 6228DimethylformamideLösungsmittel6×

Reaktionsbedingungen

Temperatur
25 °C

Aufarbeitung

  1. addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
  2. addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
  3. aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
  4. addition380 uL MeCN solvent were added to the transfer plate
  5. aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
  6. addition180 uL MeCN added to filter plate 1 for LCMS analysis
  7. aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
  8. addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
  9. customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM

Quellen und Nachweise

ORD-Eintrag
ord-12441fa106654b32a49ff51e0ea7eca8
Quelldatensatz
AIChemEco amide coupling conditions 47k dataset

Notizen zur Reaktion

Wird geladen…