3,4-Dimethoxyaniline → HCID 178492363, Verbindung
Reaktionsgleichung
COc1ccc(N)cc1OC.O=C(O)Cc1cc(F)cc(F)c1.CCN=C=NCCCN(C)C.Cl.C1=CC=C2C(=C1)C(=O)N(C2=O)O.CCN(CC)CC.CN(C)C=O>>COc1ccc(NC(=O)Cc2cc(F)cc(F)c2)cc1OCKomponenten
7
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 4
Reaktionsbedingungen
- Temperatur
- 25 °C
Aufarbeitung
- addition150 uL of MeCN/H2O (1:1) mixed solvent was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- addition150 uL of internal standard solution was dispensed separately into each plate using the 96-tip head of the Tecan Evo-200.
- aliquot10 uL aliquot taken from reaction vials, and added to pre-filled wells in the transfer plate.
- addition380 uL MeCN solvent were added to the transfer plate
- aliquot20 uL taken from transfer plate to filter plate 1 for LCMS analysis
- addition180 uL MeCN added to filter plate 1 for LCMS analysis
- aliquot10 uL taken from transfer plate to filter plate 2 for TOF-DESI analysis
- addition190 uL MeCN added to filter plate 2 for TOF-DESI analysis
- customthe 96-well filter plates were centrifuged for 2.5 min at 3000 RPM
Quellen und Nachweise
- ORD-Eintrag
- ord-5c8822f6fc4046949c07586521594b88
- Quelldatensatz
- AIChemEco amide coupling conditions 47k dataset
Notizen zur Reaktion
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