1,4-Dioxane → 1-{4-[(4-Tert-butylphenyl)sulfonyl]piperidin-1-yl}isoquinoline

Reaktionsgleichung

[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([S:11](=[O:12])(=[O:13])[CH:14]2[CH2:15][CH2:16][NH:17][CH2:18][CH2:19]2)[cH:9][cH:10]1.[CH2:40]1[O:41][CH2:42][CH2:43][O:44][CH2:45]1.[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:20][c:21]1[n:22][cH:23][cH:24][c:25]2[cH:26][cH:27][cH:28][cH:29][c:30]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8]([S:11](=[O:12])(=[O:13])[CH:14]2[CH2:15][CH2:16][N:17]([c:21]3[n:22][cH:23][cH:24][c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]34)[CH2:18][CH2:19]2)[cH:9][cH:10]1