Tert-Butylamine → 7-(tert-Butyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

HRID 82142

Reaktionsgleichung

Reaktionsgleichung von HRID 82142
Cl[C:2]1[C:7]([CH2:8][CH:9]=O)=[C:6]([Cl:11])[N:5]=[CH:4][N:3]=1.[C:12]([NH2:16])([CH3:15])([CH3:14])[CH3:13]>>[C:12]([N:16]1[C:2]2[N:3]=[CH:4][N:5]=[C:6]([Cl:11])[C:7]=2[CH:8]=[CH:9]1)([CH3:15])([CH3:14])[CH3:13]

Komponenten

3

Edukt 2

HCID 6385Tert-ButylamineHCID 13989292(4,6-Dichloropyrimidin-5-yl)acetaldehyde

Produkt 1

HCID 866720767-(tert-Butyl)-4-chloro-7H-pyrrolo[2,3-d]pyrimidine

Versuchsvorschrift

The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde and tert-butylamine to afford the title compound as a yellow liquid in 77% yield, 1.61 g.

Aufarbeitung

  1. customThe title compound was prepared

Quellen und Nachweise

ORD-Eintrag
ord-410d2a6568ab42628d46249e495fea3f
Quelldatensatz
uspto-grants-2014_09
Patentnummer
US08846698B2

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