Dichloromethane → 4-(4-bromo-1-methylpyrazol-5-yl)-N-[1-cyclohexyl-3-(1,3-dioxoisoindol-2-yl)propan-2-yl]-5-methylthiophene-2-carboxamide
Reaktionsgleichung
[Br:1][c:2]1[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:14])[OH:15])[s:10][c:11]1[CH3:12].[Br:77][P+:78]([N:79]1[CH2:80][CH2:81][CH2:82][CH2:83]1)([N:84]1[CH2:85][CH2:86][CH2:87][CH2:88]1)[N:89]1[CH2:90][CH2:91][CH2:92][CH2:93]1.[CH3:47][C:48]([O:49][C:50]([NH:51][CH:52]([C:53]([OH:54])=[O:55])[CH2:56][c:57]1[cH:58][cH:59][cH:60][cH:61][c:62]1[C:63]([F:64])([F:65])[F:66])=[O:67])([CH3:68])[CH3:69].[CH:17]([N:18]([CH2:19][CH3:20])[CH:21]([CH3:22])[CH3:23])([CH3:24])[CH3:25].[Cl:94][CH2:95][Cl:96].[NH2:26][CH:27]([CH2:28][N:29]1[C:30](=[O:39])[c:31]2[cH:32][cH:33][cH:34][cH:35][c:36]2[C:37]1=[O:38])[CH2:40][CH:41]1[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46]1.[P-:70]([F:71])([F:72])([F:73])([F:74])([F:75])[F:76]>>[Br:1][c:2]1[cH:3][n:4][n:5]([CH3:16])[c:6]1-[c:7]1[cH:8][c:9]([C:13](=[O:15])[NH:26][CH:27]([CH2:28][N:29]2[C:30](=[O:39])[c:31]3[cH:32][cH:33][cH:34][cH:35][c:36]3[C:37]2=[O:38])[CH2:40][CH:41]2[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46]2)[s:10][c:11]1[CH3:12]Komponenten
8
Edukt 7
HCID 6344Dichloromethane
HCID 9886Hexafluorophosphate
HCID 81531Diisopropylethylamine
HCID 2733180Bromotripyrrolidin-1-ylphosphonium
HCID 44446362-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[2-(trifluoromethyl)phenyl]propanoic Acid
HCID 578265224-(4-bromo-1-methyl-1H-pyrazol-5-yl)-5-methyl-2-thiophenecarboxylic acid
