Hydrogen Bromide → 5-{2-[6-(2-Ethyl-5-fluoro-4-hydroxy-phenyl)-1H-indazol-3-yl]-4,5,7,8-tetrahydro-1H-imidazo[4,5-d]azepine-6-carbonyl}-pyridine-2-carbonitrile
Reaktionsgleichung
[BrH:1].[BrH:2].[BrH:3].[C:33](#[N:34])[c:35]1[n:36][cH:37][c:38]([C:39](=[O:40])[Cl:41])[cH:42][cH:43]1.[C:53](=[O:54])([O-:55])[OH:56].[CH2:4]([CH3:5])[c:6]1[c:7](-[c:14]2[cH:15][cH:16][c:17]3[c:18](-[c:23]4[n:24][c:25]5[c:26]([nH:32]4)[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]5)[n:19][nH:20][c:21]3[cH:22]2)[cH:8][c:9]([F:13])[c:10]([OH:12])[cH:11]1.[CH:44]([N:45]([CH2:46][CH3:47])[CH:48]([CH3:49])[CH3:50])([CH3:51])[CH3:52].[Na+:57].[O:58]=[CH:59][N:60]([CH3:61])[CH3:62]>>[CH2:4]([CH3:5])[c:6]1[c:7](-[c:14]2[cH:15][cH:16][c:17]3[c:18](-[c:23]4[n:24][c:25]5[c:26]([nH:32]4)[CH2:27][CH2:28][N:29]([C:39]([c:38]4[cH:37][n:36][c:35]([C:33]#[N:34])[cH:43][cH:42]4)=[O:40])[CH2:30][CH2:31]5)[n:19][nH:20][c:21]3[cH:22]2)[cH:8][c:9]([F:13])[c:10]([OH:12])[cH:11]1
