Piperidine → 4-Piperidinylbut-1-ene

HRID 8380

Reaktionsgleichung

Reaktionsgleichung von HRID 8380
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

3

Edukt 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

Produkt 1

HCID 45622824-Piperidinylbut-1-eneAusbeute 93,4 %

Versuchsvorschrift

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

Aufarbeitung

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

Quellen und Nachweise

ORD-Eintrag
ord-d7ef957ab1cf46f68f1f4c42cdc7ceea
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07087757B2

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