3,3-Dimethoxy-pyrrolidine benzyl carbamate → 3,3-Dimethoxypyrrolidine

HRID 846687

Reaktionsgleichung

Reaktionsgleichung von HRID 846687
C(NC(=O)O)C1C=CC=CC=1.[CH3:12][O:13][C:14]1([O:19][CH3:20])[CH2:18][CH2:17][NH:16][CH2:15]1.[H][H]>CO.[Pd]>[CH3:12][O:13][C:14]1([O:19][CH3:20])[CH2:18][CH2:17][NH:16][CH2:15]1

Komponenten

5

Edukt 2

HCID 867460613,3-Dimethoxy-pyrrolidine benzyl carbamateHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 110298823,3-Dimethoxypyrrolidine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

The 2.21 g of 3,3-dimethoxy-pyrrolidine benzyl carbamate, from step 3, dissolved in 100 mL of methanol, 2.21 g of Pd/C (wet) was added, and placed under 4 atm of hydrogen for 20 hours. The catalyst was filtered off using a 0.45 micro millipore filter and the solvent was evaporated to afford the title compound.

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. filtrationfilter
  3. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-8db8cb3449b64d54a778053f320dfcbb
Quelldatensatz
uspto-grants-1992_08
Patentnummer
US05137892

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