Chloroacetic Acid → 2,4,6-Trichlorophenoxyacetic acid

HRID 847120

Reaktionsgleichung

Reaktionsgleichung von HRID 847120
[OH-].[Na+].[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[C:5]=1[OH:12].Cl[CH2:14][C:15]([OH:17])=[O:16].Cl>O>[Cl:3][C:4]1[CH:9]=[C:8]([Cl:10])[CH:7]=[C:6]([Cl:11])[C:5]=1[O:12][CH2:14][C:15]([OH:17])=[O:16]

Komponenten

6

Edukt 4

HCID 300Chloroacetic AcidHCID 313Hydrochloric AcidHCID 69142,4,6-TrichlorophenolHCID 14798Sodium Hydroxide

Produkt 1

HCID 113312,4,6-Trichlorophenoxyacetic acidAusbeute 92,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

26.4 g (0.66 mol) of sodium hydroxide and 59.1 g (0.299 mol) of 2,4,6-trichlorophenol were respectively added to 450 ml of water for dissolution at normal temperature. Adding 28.11 g (0.299 mol) of monochloroacetic acid hereto, the reaction mixture was heated and refluxed for 9 to 10 hours, while the external temperature was maintained at 110°-120° C. On completion of the reaction, it was lowered to normal temperature to be followed by the filtration of product precipitate. The above reaction product was dissolved in 100 g of water and acidified with concentrated hydrochloric acid to obtain 70.5 g of 2,4,6-trichloropnenoxyacetic acid as a raw product.

Aufarbeitung

  1. temperaturethe reaction mixture was heated
  2. temperaturerefluxed for 9 to 10 hours, while the external temperature
  3. temperaturewas maintained at 110°-120° C
  4. customOn completion of the reaction, it
  5. filtrationto be followed by the filtration of product precipitate
  6. customThe above reaction product

Quellen und Nachweise

ORD-Eintrag
ord-99da688b1c7047149e6dfb8d4b720759
Quelldatensatz
uspto-grants-1992_08
Patentnummer
US05139564

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