Water → 1-(5-Tert-Butoxycarbonyl-2-Nitrophenoxy)-2-(5-Methyl-2-Nitrophenoxy)Ethane

Beteiligte Stoffe

Reaktionsschritte

A mixture of Compound 3e (239 mg, 1 mmol), 1-bromo-2-(5-methyl-2-nitrophenoxy)ethane, see G. Grynkiewicz, et al. (1985), (286 mg, 1.1 mmol), K2CO3 (83 mg, 0.6 mmol) in dry N-methylpyrrolidinone (0.75 mL) was heated at 140° C. for 10 min with protection from moisture, cooled and H2O added dropwise to precipitate the product, Compound 3f. After filtration, recrystallization from EtOH gave a white solid, m.p. 113°-114° C. Yield, 383 mg (92%).

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