4-((Dimethylamino)methyl)benzonitrile → HCID 19881402, Verbindung

HRID 847414Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 847414
[CH:1]1[C:18]2[C:5](=[C:6]([C:19]3[CH:26]=[CH:25][CH:24]=[CH:23][C:20]=3[CH2:21][Br:22])[C:7]3[C:16]([CH:17]=2)=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[CH3:27][N:28]([CH2:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]#[N:38])=[CH:33][CH:32]=1)[CH3:29].[PH4+].[AsH4+]>C(#N)C.C(OCC)C>[Br-:22].[C:37]([C:34]1[CH:33]=[CH:32][C:31]([CH2:30][N+:28]([CH2:21][C:20]2[CH:23]=[CH:24][CH:25]=[CH:26][C:19]=2[C:6]2[C:7]3[C:16](=[CH:15][C:14]4[C:9]([CH:8]=3)=[CH:10][CH:11]=[CH:12][CH:13]=4)[CH:17]=[C:18]3[C:5]=2[CH:4]=[CH:3][CH:2]=[CH:1]3)([CH3:27])[CH3:29])=[CH:36][CH:35]=1)#[N:38]

Komponenten

7

Edukt 4

HCID 8263294-((Dimethylamino)methyl)benzonitrileHCID 5460504PhosphoniumHCID 5460506ArsoniumHCID 19881404HCID 19881404, Verbindung

Produkt 1

HCID 19881402HCID 19881402, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A mixture of (B) and N,N-dimethyl-4-cyano benzylamine in acetonitrile was refluxed for 2 hours. The reaction mixture was then poured into diethyl ether, and the crude product was collected by filtration. The crude product was recrystallized from ethanol. The same reaction can be used to prepare the corresponding phosphonium and arsonium salts.

Aufarbeitung

  1. temperaturewas refluxed for 2 hours
  2. filtrationthe crude product was collected by filtration
  3. customThe crude product was recrystallized from ethanol
  4. customThe same reaction

Quellen und Nachweise

ORD-Eintrag
ord-c99f46cb7eb8477eb0e8a2917d7c6568
Quelldatensatz
uspto-grants-1992_08
Patentnummer
US05141969

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