Water → 3-Chloro-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=[C:10](O)[C:9]2=[O:19])=[CH:4][CH:3]=1.O.P(Cl)(Cl)([Cl:23])=O>>[Cl:23][C:10]1[C:9](=[O:19])[N:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:17]2[C:12]([N:11]=1)=[CH:13][CH:14]=[CH:15][CH:16]=2Komponenten
4
Versuchsvorschrift
A solution of 1-(4-chlorophenyl)-1,2-dihydro-3-hydroxyquinoxalin-2-one (20 g) in phosphorus oxychloride (64 ml) was refluxed for 4 hours and then poured slowly into iced water. The resulting solid was filtered off, triturated with pentane and dried giving the title compound (19.4 g) mp>300° C.
Aufarbeitung
- filtrationThe resulting solid was filtered off
- customtriturated with pentane