Potassium Carbonate → HCID 18800645, Verbindung

HRID 849085Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 849085
[C:1]([CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11])([O:3][CH3:4])=[O:2].Br[CH2:13][CH2:14][CH:15]1[O:19][CH2:18][CH2:17][O:16]1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C.O>[O:16]1[CH2:17][CH2:18][O:19][CH:15]1[CH2:14][CH2:13][C:5]1([C:1]([O:3][CH3:4])=[O:2])[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11]

Komponenten

6

Edukt 3

HCID 11430Potassium CarbonateHCID 877762-(2-Bromoethyl)-1,3-dioxolaneHCID 170489Cyclohexanecarboxylic acid, 2-oxo-, methyl ester

Produkt 1

HCID 18800645HCID 18800645, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

A solution of 2-carbomethoxycyclohexanone (2.0 g, 12.8 mmoles) in 50 mL of DMF was reacted at 70° C. for 15 h with 2-(2-bromoethyl)-1,3-dioxolane (4.6 g, 25 moles) and potassium carbonate (4.8 g, 34.8 mmoles). The reaction mixture was diluted to 500 mL with water and extracted with ethyl ether/ethyl acetate. The organic extracts were dried over sodium sulfate, and the solvent was evaporated to generate the title compound as an oil.

Aufarbeitung

  1. extractionextracted with ethyl ether/ethyl acetate
  2. dry with materialThe organic extracts were dried over sodium sulfate
  3. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-fee485bb624b42ff99cd221a42969cd4
Quelldatensatz
uspto-grants-2000_01
Patentnummer
US06011028

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