3-Amino-1-propanol → HCID 19369798, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[N:10]1[C:22]2[C:21]3[CH:20]=[CH:19][CH:18]=[C:17]([O:23][C:24]([F:27])([F:26])[F:25])[C:16]=3[N:15]=[C:14](Cl)[C:13]=2[CH2:12][CH2:11]1.[NH2:29][CH2:30][CH2:31][CH2:32][OH:33]>>[CH3:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[N:10]1[C:22]2[C:21]3[CH:20]=[CH:19][CH:18]=[C:17]([O:23][C:24]([F:27])([F:26])[F:25])[C:16]=3[N:15]=[C:14]([NH:29][CH2:30][CH2:31][CH2:32][OH:33])[C:13]=2[CH2:12][CH2:11]1Komponenten
3
Versuchsvorschrift
1-(2-Methyl-4-methoxyphenyl)-4-chloro-6-trifluoromethoxy-2,3-dihydropyrrolo[3,2-c]quinoline(550 mg, 1.3 mmol) was dissolved in 3-amino-1-propanol(10 ml) in the pressure tube, and reacted at the same condition of Step 3 in the Example 23 to obtain 400 mg of desired compound as solid in 67% of yield.
Aufarbeitung
- customreacted at the same condition of Step 3 in the Example 23
Quellen und Nachweise
- ORD-Eintrag
- ord-b3f8ba86f8c1493bb10b432a24a23cd6
- Quelldatensatz