Potassium Hydroxide → Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

HRID 850334Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 850334
[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].[OH-].[K+]>C1C=CC=CC=1.O.[Fe-3](C#N)(C#N)(C#N)(C#N)(C#N)C#N.[K+].[K+].[K+]>[C:12]([C:9]1[C:10](=[O:11])[C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:6][C:7](=[CH:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=1)([CH3:13])([CH3:14])[CH3:15]

Komponenten

6

Edukt 2

HCID 14797Potassium HydroxideHCID 13908126Ethyl (3,5-di-t-butyl-4-hydroxyphenyl)-acetate

Produkt 1

HCID 22019852Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 178511488HCID 178511488, VerbindungKatalysatorHCID 241BenzeneLösungsmittelHCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
40 °C

Versuchsvorschrift

In benzene (150 mL) was dissolved Intermediate 10 (6.7 g, 22.9 mmol) and this treated with a solution of potassium hydroxide (13.9 g [85%], 210 mmol) and potasium ferricyanide (K3Fe(CN)6) (15.2 g, 46 mmol) in water (150 mL). The mixture stirred under nitrogen atmosphere at 40° C. for 2 hours. The benzene layer then separated, washed with brine (100 mL) and dried over magnesium sulfate. The solvent was evaporated in vacuo to give a red oil, 6.1 g (92%), which was used as is.

Aufarbeitung

  1. customThe benzene layer then separated
  2. washwashed with brine (100 mL)
  3. dry with materialdried over magnesium sulfate
  4. customThe solvent was evaporated in vacuo
  5. customto give a red oil, 6.1 g (92%), which

Quellen und Nachweise

ORD-Eintrag
ord-4eae0ab84fa34408a0f311abf2920d41
Quelldatensatz
uspto-grants-2000_01
Patentnummer
US06017918

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