Hydrazine hydrate (1:1) → HCID 69414151, Verbindung

HRID 851891Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 851891
[O:1]=[S:2]1(=[O:26])[C:7]2[CH:8]=[C:9]([O:12][C:13]3[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=3)[C:16](OC)=[O:17])[CH:10]=[CH:11][C:6]=2[N:5]2[CH2:23][CH2:24][CH2:25][C:4]2=[N:3]1.O.[NH2:28][NH2:29]>CO.CN(C=O)C>[O:1]=[S:2]1(=[O:26])[C:7]2[CH:8]=[C:9]([O:12][C:13]3[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=3)[C:16]([NH:28][NH2:29])=[O:17])[CH:10]=[CH:11][C:6]=2[N:5]2[CH2:23][CH2:24][CH2:25][C:4]2=[N:3]1

Komponenten

5

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 69414424HCID 69414424, Verbindung

Produkt 1

HCID 69414151HCID 69414151, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

A suspension of 500 mg (1.34 mmol) of the product obtained in Step A and 978 μl (20.13 mmol) of hydrazine monohydrate in a mixture of MeOH (30 ml) and DMF (6 ml) is refluxed for 24 hours. The MeOH is evaporated off, water is added to the reaction mixture and the precipitate, which corresponds to the title product, is filtered off.

Aufarbeitung

  1. temperatureis refluxed for 24 hours
  2. customThe MeOH is evaporated off
  3. additionwater is added to the reaction mixture
  4. filtrationis filtered off

Quellen und Nachweise

ORD-Eintrag
ord-862ff0c4f81b44cbb184e5c07dd910c3
Quelldatensatz
uspto-grants-2007_08
Patentnummer
US07253163B2

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