Methanesulfonyl chloride → Methanesulfonic acid 1-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-cyclobutylmethyl ester
Reaktionsgleichung
[F:1][C:2]([F:20])([F:19])[O:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]#[C:11][CH2:12][C:13]2([CH2:17][OH:18])[CH2:16][CH2:15][CH2:14]2)=[CH:6][CH:5]=1.[CH3:21][S:22](Cl)(=[O:24])=[O:23]>>[F:1][C:2]([F:19])([F:20])[O:3][C:4]1[CH:5]=[CH:6][C:7]([C:10]#[C:11][CH2:12][C:13]2([CH2:17][O:18][S:22]([CH3:21])(=[O:24])=[O:23])[CH2:14][CH2:15][CH2:16]2)=[CH:8][CH:9]=1Komponenten
3
Versuchsvorschrift
In analogy to the procedure described in example 1G], {1-[3-(4-trifluoromethoxy-phenyl)-prop-2-ynyl]-cyclobutyl}-methanol and methanesulfonyl chloride gave the title compound as yellow oil.
Quellen und Nachweise
- ORD-Eintrag
- ord-c4443b14174d460e8165823911fbba34
- Quelldatensatz
- uspto-grants-2007_08