HCID 91379151, Verbindung → HCID 91430685, Verbindung

HRID 857370Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 857370
[CH3:1][O:2][C:3](=[O:22])[CH2:4][CH:5]1[C:9]2=[CH:10][C:11]3[C:12]([C:19]([CH3:21])=[CH2:20])=[CH:13][C:14]([O:17][CH3:18])=[CH:15][C:16]=3[N:8]2[CH2:7][CH2:6]1>CCO.[Pd]>[CH3:1][O:2][C:3](=[O:22])[CH2:4][CH:5]1[C:9]2=[CH:10][C:11]3[C:12]([CH:19]([CH3:20])[CH3:21])=[CH:13][C:14]([O:17][CH3:18])=[CH:15][C:16]=3[N:8]2[CH2:7][CH2:6]1

Komponenten

4

Edukt 1

HCID 91379151HCID 91379151, Verbindung

Produkt 1

HCID 91430685HCID 91430685, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To the compound of Step 1 (200 mg, 0.67 mmol) in EtOH (20 mL) was added Pd/C 10% (100 mg). The mixture was hydrogenated with a Parr hydrogenator at 50 psi for 45 minutes the filtered on a pad of celite. The filtrate was evaporated to dryness and used as such in the next step (170 mg).

Aufarbeitung

  1. filtrationthe filtered on a pad of celite
  2. customThe filtrate was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-d7682efbd2dd4ee5bcddf5220621f35b
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07144913B2

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