Hydrazine hydrate (1:1) → Diethyl [(6-amino-3-chloro-2-pyridinyl)methyl]phosphonate
Reaktionsgleichung
[Cl:1][C:2]1[C:3]([CH2:19][P:20](=[O:27])([O:24][CH2:25][CH3:26])[O:21][CH2:22][CH3:23])=[N:4][C:5]([N:8]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:6][CH:7]=1.O.NN>C(Cl)Cl>[NH2:8][C:5]1[N:4]=[C:3]([CH2:19][P:20](=[O:27])([O:24][CH2:25][CH3:26])[O:21][CH2:22][CH3:23])[C:2]([Cl:1])=[CH:7][CH:6]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Following the procedure from Example 16, the product from Example 27 (1.0 g, 2.4 mmol) was reacted with hydrazine monohydrate (0.121 g, 2.4 mmol) in CH2Cl2 (25 mL). Workup produced the crude title product which was used without further purification.
Quellen und Nachweise
- ORD-Eintrag
- ord-1a8aca07cf36418c929108cb02a5ad2d
- Quelldatensatz
- uspto-grants-1998_02
- Patentnummer
- US05716964
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