Benzyl Bromide → 3(R)-Benzyl-5(S)-[5-benzyloxy-1(S)-tert-butoxycarbonylamino-3,3-dimethyl-pentyl]-2-oxotetrahydrofuran

Reaktionsgleichung

[CH2:1]([O:8][CH2:9][CH2:10][C:11]([CH3:29])([CH3:28])[CH2:12][C@@H:13]([C@H:22]1[O:26][C:25](=[O:27])[CH2:24][CH2:23]1)[NH:14][C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C[Si]([N-][Si](C)(C)C)(C)C.[Li+].[CH2:40](Br)[C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1>O1CCCC1>[CH2:40]([C@@H:24]1[CH2:23][C@@H:22]([C@@H:13]([NH:14][C:15]([O:17][C:18]([CH3:20])([CH3:21])[CH3:19])=[O:16])[CH2:12][C:11]([CH3:29])([CH3:28])[CH2:10][CH2:9][O:8][CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[O:26][C:25]1=[O:27])[C:41]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:42]=1