Sodium Hydroxide → Benzaldehyde (2-phenylethyl)hydrazone

HRID 863708Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 863708
[OH-].[Na+].S(O)(O)(=O)=O.[C:8]1([CH2:14][CH2:15][NH:16][NH2:17])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:8]1([CH2:14][CH2:15][NH:16][N:17]=[CH:14][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Komponenten

3

Edukt 2

HCID 14798Sodium Hydroxide2×HCID 61100Phenelzine Sulfate

Produkt 1

HCID 67615296Benzaldehyde (2-phenylethyl)hydrazoneAusbeute 163,4 %

Versuchsvorschrift

100 ml of aqueous 10% sodium hydroxide solution were added to an aqueous solution (50 ml) of 14.55 g of (2-phenylethyl)hydrazine sulfate, and 2.25 g of sodium hydroxide were added thereto and stirred at room temperature for one hour. The reaction solution was extracted with 250 ml of dichloromethane, dried over magnesium sulfate, concentrated under reduced pressure and dried. The resulting residue was dissolved in 100 ml of ethanol, and 5.55 g of benzaldehyde were added thereto and heated under reflux for 6 hours. This reaction solution was concentrated under reduced pressure and dried to obtain 11.38 g of a crude product of the intended compound as an yellow oil.

Aufarbeitung

  1. additionwere added
  2. extractionThe reaction solution was extracted with 250 ml of dichloromethane
  3. dry with materialdried over magnesium sulfate
  4. concentrationconcentrated under reduced pressure
  5. customdried
  6. dissolutionThe resulting residue was dissolved in 100 ml of ethanol
  7. addition5.55 g of benzaldehyde were added
  8. temperatureheated
  9. temperatureunder reflux for 6 hours
  10. concentrationThis reaction solution was concentrated under reduced pressure
  11. customdried

Quellen und Nachweise

ORD-Eintrag
ord-f0a8bbf0bab84ba8934132205d24a395
Quelldatensatz
uspto-grants-1998_02
Patentnummer
US05721264

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