Triethylamine → HCID 19418948, Verbindung

HRID 864476Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 864476
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[OH:6][CH2:7][CH2:8][N:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[S:11][C:10]1=[O:18].C(N(CC)CC)C>ClCCl>[S:2]([O:6][CH2:7][CH2:8][N:9]1[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[S:11][C:10]1=[O:18])([CH3:1])(=[O:4])=[O:3]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 2721073-(2-Hydroxyethyl)-1,3-benzothiazol-2(3H)-one

Produkt 1

HCID 19418948HCID 19418948, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

Methanesulfonyl chloride (1.625 ml, 2.4 g, 21 mmol) in dichloromethane (10 ml) was added dropwise with stirring to 3-(2-hydroxyethyl)benzothiazolin-2-one (3.9 g, 20 mmol) (J. J. D'Amico and F. G. Bollinger; J. Heterocyclic Chemistry 1988, 25, 1601).and triethylamine (3.478 ml, 2.525 g, 25 mmol) in dichloromethane (80 ml) and stirred for one hour at room temperature. The reaction mixture was then washed with water and dried (MgSO4), filtered and the solvent evaporated in-vacuo to give the title product.

Aufarbeitung

  1. washThe reaction mixture was then washed with water
  2. dry with materialdried (MgSO4)
  3. filtrationfiltered
  4. customthe solvent evaporated in-vacuo

Quellen und Nachweise

ORD-Eintrag
ord-29298d48e9284d049fee26defbd9df5e
Quelldatensatz
uspto-grants-1996_10
Patentnummer
US05563147

Notizen zur Reaktion

Wird geladen…