Diacetylguanine → N-(6,7-dihydro-6-oxo-1H-purin-2-yl)acetamide

HRID 865353

Reaktionsgleichung

Reaktionsgleichung von HRID 865353
[C:1]([N:4](C(=O)C)[C:5]1[NH:6][C:7](=[O:14])[C:8]2[NH:9][CH:10]=[N:11][C:12]=2[N:13]=1)(=[O:3])[CH3:2]>O.CO>[C:1]([NH:4][C:5]1[NH:6][C:7](=[O:14])[C:8]2[NH:9][CH:10]=[N:11][C:12]=2[N:13]=1)(=[O:3])[CH3:2]

Komponenten

4

Edukt 1

HCID 136360183Diacetylguanine

Produkt 1

HCID 135432176N-(6,7-dihydro-6-oxo-1H-purin-2-yl)acetamide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

Diacetylguanine (3 g) was refluxed in a mixture of water (5 ml) and methanol (50 ml) for 4 hours. The solvents were then removed under reduced pressure, the residue washed with cold methanol, and dried under vacuum, to give N-acetylguanine, a compound of Formula (1a).

Aufarbeitung

  1. customThe solvents were then removed under reduced pressure
  2. washthe residue washed with cold methanol
  3. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-f6eba9ba852344f6a1ee68dbdc1a61a4
Quelldatensatz
uspto-grants-1996_10
Patentnummer
US05565565

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