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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 865518Erstellt: 25. Oktober 2026

Tetrabutylammonium Fluoride → 2,6-Dipropyl-4-(2-hydroxyethyl)phenol

https://huagongshe.com/reaction/865518

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTetrabutylammonium FluorideHCID 2724141—
Eduktt-Butyldimethylsilyloxy-2,6-dipropyl-4-(2-hydroxyethyl)-benzeneHCID 19080442—
LösungsmittelTetrahydrofuranHCID 8028—
Produkt2,6-Dipropyl-4-(2-hydroxyethyl)phenolHCID 19080373—

Reaktionsschritte

To a solution of 1.0 g (2.98 mrnol) of the product of Step C in 3.0 mL of THF was added 3.57 mL (3.57 mmol) of 1.0 N solution of tetrabutylammonium fluoride in THF. After 15 minutes TLC indicated that the reaction was complete. The reaction mixture was concentrated and then purified by flash chromatography (silica gel, hexane/ethyl acetate 3:1) to give 1.13 g of the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05565485
Quelldatensatzuspto-grants-1996_10
ORD IDord-358f89dd7cad4de78ad84ce485f328f1
Quellennotizuspto-grants-1996_10