Boron tribromide → 2,3-Dihydro-1,4-benzodioxin-5-ol

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

At 0° C., boron tribromide (5.6 cm3) is added slowly to a solution of 5-methoxy-1,4-benzodioxane (5 g, 30.1 mmol) in 25 cm3 of CH2Cl2. The mixture is stirred at 0° C. for 15 min, the solution is then hydrolysed with 10 cm3 of water and the product is extracted with CH2Cl2. Purification on a silica column (eluent: 100% CH2Cl2) enables 4.49 g of a colorless oil to be obtained.

Herkunft & Nachweise