反应详情

温度

0 °C

At 0° C., boron tribromide (5.6 cm3) is added slowly to a solution of 5-methoxy-1,4-benzodioxane (5 g, 30.1 mmol) in 25 cm3 of CH2Cl2. The mixture is stirred at 0° C. for 15 min, the solution is then hydrolysed with 10 cm3 of water and the product is extracted with CH2Cl2. Purification on a silica column (eluent: 100% CH2Cl2) enables 4.49 g of a colorless oil to be obtained.

1. extractionhydrolysed with 10 cm3 of water and the product is extracted with CH2Cl2
2. customPurification on a silica column (eluent: 100% CH2Cl2)
3. customto be obtained