Ethanol → Ethyl 2-hydroxy-2-phenylpropanoate

HRID 866002

Reaktionsgleichung

Reaktionsgleichung von HRID 866002
[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH2:18](O)[CH3:19]>CCOCC>[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([O:10][CH2:18][CH3:19])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 1303Atrolactic acid

Produkt 1

HCID 6429709Ethyl 2-hydroxy-2-phenylpropanoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

(±)-Phenyllactic acid (4.96 g) and 1/2 ml concentrated sulfuric acid in 150 ml absolute ethanol is refluxed for 18 hours. Solvent is stripped, the residue is dissolved in ether, and extracted with saturated sodium bicarbonate solution. The ether is dried, filtered, and stripped to leave (±)-ethyl phenyllactate. NMR (CDCl3): δ1.3 (t, 3H), 3.0(d of d, 1H), 3.1 (d of d, 1H), 4.2 (q, 2H), 4.4 (d of d, 1H), 7.3 (m, 5H).

Aufarbeitung

  1. extractionextracted with saturated sodium bicarbonate solution
  2. dry with materialThe ether is dried
  3. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-4da8ca9e64d34f87bdf406815196a29d
Quelldatensatz
uspto-grants-1996_10
Patentnummer
US05569674

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