HCID 14075472, Verbindung → N,N-Diethyl-3-pyrrolidinemethanamine

HRID 868141

Reaktionsgleichung

Reaktionsgleichung von HRID 868141
[CH2:1]([N:3]([CH2:17][CH3:18])[CH2:4][CH:5]1[CH2:9][CH2:8][N:7](CC2C=CC=CC=2)[CH2:6]1)[CH3:2].[H][H]>[Pd].CO>[CH2:17]([N:3]([CH2:1][CH3:2])[CH2:4][CH:5]1[CH2:9][CH2:8][NH:7][CH2:6]1)[CH3:18]

Komponenten

5

Edukt 2

HCID 14075472HCID 14075472, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 14075474N,N-Diethyl-3-pyrrolidinemethanamineAusbeute 101,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A mixture of 25.4 g (0.10 mole) of N,N-diethyl-1-(phenylmethyl)-3-pyrrolidinemethanamine, 200 ml of methyl alcohol, 2 g of palladium on carbon and hydrogen were shaken at a pressure of 51.5 psi. After 20.3 hours, the catalyst was filtered and the filtrate concentrated under reduced pressure. The residue was bulb to bulb distilled giving 15.9 g of N,N-diethyl-3-pyrrolidinemethanamine.

Aufarbeitung

  1. filtrationthe catalyst was filtered
  2. concentrationthe filtrate concentrated under reduced pressure
  3. distillationdistilled

Quellen und Nachweise

ORD-Eintrag
ord-ba76fa491f504560a6f9994f141446a8
Quelldatensatz
uspto-grants-1988_10
Patentnummer
US04777175

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