ethyl 2-((E)-4-methoxybenzylidene)butyrate → HCID 14329809, Verbindung

HRID 868225Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 868225
[H-].[Al+3].[Li+].[H-].[H-].[H-].[CH3:7][O:8][C:9]1[CH:23]=[CH:22][C:12](/[CH:13]=[C:14](\[CH2:20][CH3:21])/[C:15](OCC)=[O:16])=[CH:11][CH:10]=1>CCOCC>[CH3:7][O:8][C:9]1[CH:23]=[CH:22][C:12](/[CH:13]=[C:14](\[CH2:20][CH3:21])/[CH2:15][OH:16])=[CH:11][CH:10]=1

Komponenten

4

Edukt 2

HCID 10933410ethyl 2-((E)-4-methoxybenzylidene)butyrateHCID 21226445Aluminium lithium hydride2×

Produkt 1

HCID 14329809HCID 14329809, VerbindungAusbeute 83,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel3×

Versuchsvorschrift

To a suspension of lithium aluminum hydride (3 g) in dry ether (300 ml) was added a solution of ethyl 2-((E)-4-methoxybenzylidene)butyrate (19 g) in dry ether (30 ml) at 0° C. with stirring. The mixture was stirred at the same temperature for 3 hours and excess lithium aluminum hydride was decomposed with wet ether. The reaction mixture was filtered and the filtrate was washed with water, dried over magnesium sulfate and then evaporated to dryness to give 2-((E)-4-methoxybenzylidene)butan-1-ol (13 g).

Aufarbeitung

  1. stirringThe mixture was stirred at the same temperature for 3 hours
  2. filtrationThe reaction mixture was filtered
  3. washthe filtrate was washed with water
  4. dry with materialdried over magnesium sulfate
  5. customevaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-0afb132d3f28440b86adbd910fe358a1
Quelldatensatz
uspto-grants-1988_10
Patentnummer
US04778804

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