Ammonia → HCID 23371316, Verbindung
Reaktionsgleichung
[NH2:1][C:2]1[C:3]([SH:9])=[N:4][C:5]([Cl:8])=[CH:6][CH:7]=1.N.[CH:11](O)=O>>[Cl:8][C:5]1[N:4]=[C:3]2[S:9][CH:11]=[N:1][C:2]2=[CH:7][CH:6]=1Komponenten
4
Versuchsvorschrift
3-Amino-6-chloropyridine-2-thiol (Q-3) (16.4 g, 103 mmol) in formic acid (80 mL) was refluxed at 110° C. for 2 h. The reaction mixture was cooled and neutralized with concentrated ammonia to pH 7. A precipitate was collected by filtration as the title compound (14.5 g). MS (m/z): 171 (M+1)+.
Aufarbeitung
- temperatureThe reaction mixture was cooled
- filtrationA precipitate was collected by filtration as the title compound (14.5 g)
Quellen und Nachweise
- ORD-Eintrag
- ord-d2d324eec49e4a3ba1c7a992cb56d34e
- Quelldatensatz
- uspto-grants-2015_03
- Patentnummer
- US08987269B2
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