Ammonium Chloride → 3-{3'-[(3-Methanesulfonyl-5-trifluoromethyl-benzoyl)-methyl-amino]-[3,4']bipyridinyl-2-yloxy}-azetidine-1-carboxylic acid tert-butyl ester

Reaktionsgleichung

[CH3:1][NH:2][C:3]1[CH:4]=[N:5][CH:6]=[CH:7][C:8]=1[C:9]1[C:10]([O:15][CH:16]2[CH2:19][N:18]([C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:17]2)=[N:11][CH:12]=[CH:13][CH:14]=1.FC1C=CC=C(OC)C=1C1C=CN=CC=1N(CC(F)(F)F)[C:43](=[O:58])[C:44]1[CH:49]=[C:48]([C:50]([F:53])([F:52])[F:51])[CH:47]=[C:46]([S:54]([CH3:57])(=[O:56])=[O:55])[CH:45]=1.CCN(C(C)C)C(C)C.CS(C1C=C(C=C(C(F)(F)F)C=1)C(Cl)=O)(=O)=O.[NH4+].[Cl-]>C(Cl)Cl>[C:23]([O:22][C:20]([N:18]1[CH2:19][CH:16]([O:15][C:10]2[C:9]([C:8]3[CH:7]=[CH:6][N:5]=[CH:4][C:3]=3[N:2]([C:43](=[O:58])[C:44]3[CH:49]=[C:48]([C:50]([F:53])([F:51])[F:52])[CH:47]=[C:46]([S:54]([CH3:57])(=[O:56])=[O:55])[CH:45]=3)[CH3:1])=[CH:14][CH:13]=[CH:12][N:11]=2)[CH2:17]1)=[O:21])([CH3:26])([CH3:25])[CH3:24]