Pyridine → 8-Dodecen-1-ol, 1-acetate, (8Z)-

Reaktionsgleichung

[CH:1](=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10]/[CH:11]=[CH:12]\CCCC.[CH3:18][C:19](OC(C)=O)=[O:20].N1C=CC=CC=1.C(O)CCCCCC/C=C\CCC>>[C:19]([O:17][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]/[CH:8]=[CH:9]\[CH2:10][CH2:11][CH3:12])(=[O:20])[CH3:18]

Komponenten

Edukt 4

HCID 1049Pyridine

HCID 7918Acetic Anhydride

HCID 52832958-Dodecen-1-ol, (8Z)-

HCID 536449511-Hexadecenal, (11Z)-

Produkt 1

HCID 53633778-Dodecen-1-ol, 1-acetate, (8Z)-Ausbeute 90 %

Versuchsvorschrift

By acetylation of compound 2: According to the procedure for compound 6, Ac2O (0.29 mL, 3.0 mmol), pyridine (0.14 mL, 1.8 mmol), and alcohol 12 (0.28 g, 1.5 mmol) were reacted to provide 13 (19 g, 90% yield, 86% Z as determined by 1H-NMR) as a colorless oil.