Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 879892

Reaktionsgleichung

Reaktionsgleichung von HRID 879892
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

Produkt 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vaccuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

Aufarbeitung

  1. customSolvents were evaporated
  2. customdried under vaccuo

Quellen und Nachweise

ORD-Eintrag
ord-a278cc7d859c47cfa5722c2190158b6e
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08987295B2

Verknüpfte Notizen

Wird geladen…