4-Ethoxyphenol → 2-Bromo-4-ethoxyphenol

HRID 879986

Reaktionsgleichung

Reaktionsgleichung von HRID 879986
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][C:7]([OH:10])=[CH:6][CH:5]=1)[CH3:2].[Br:11]Br>C(Cl)(Cl)Cl>[Br:11][C:8]1[CH:9]=[C:4]([O:3][CH2:1][CH3:2])[CH:5]=[CH:6][C:7]=1[OH:10]

Komponenten

4

Edukt 2

HCID 121504-EthoxyphenolHCID 24408Bromine

Produkt 1

HCID 230482822-Bromo-4-ethoxyphenol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Versuchsvorschrift

To a solution of 4-(ethyloxy)phenol (Commercial eg Aldrich) (1.0 g) in chloroform (5 ml) cooled to 0° C. was added bromine (1.26 g) dropwise over 20 min. The resulting mixture was stirred at 25 C for 2 h, before washing sequentially with aqueous sodium bicarbonate, and brine. The organics were dried over sodium sulphate, filtered and concentrated in vacuo to yield the title compound, 1.8 g

Aufarbeitung

  1. washbefore washing sequentially with aqueous sodium bicarbonate, and brine
  2. dry with materialThe organics were dried over sodium sulphate
  3. filtrationfiltered
  4. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-4c44dc31bdd64395a0330d2f20d4f8a3
Quelldatensatz
uspto-grants-2015_03
Patentnummer
US08993560B2

Verknüpfte Notizen

Wird geladen…