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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 885376Erstellt: 25. Oktober 2026

Lithium Hydroxide → {3-[4-Bromo-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-5-chloro-phenyl}-acetic acid

https://huagongshe.com/reaction/885376

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktLithium HydroxideHCID 3939—
Edukt{3-[4-Bromo-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-5-chloro-phenyl}-acetic acid ethyl esterHCID 58237451—
LösungsmittelMethanolHCID 887—
LösungsmittelWaterHCID 962—
Produkt{3-[4-Bromo-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-5-chloro-phenyl}-acetic acidHCID 44187351—

Reaktionsbedingungen

Temperatur60 °C

Reaktionsschritte

{3-[4-Bromo-2-(2-oxo-oxazolidin-3-ylmethyl)-phenoxy]-5-chloro-phenyl}-acetic acid ethyl ester (0.06 g, 0.13 mmol) in MeOH and H2O was treated with lithium hydroxide, and the reaction was stirred at 60° C. for 30 minutes to give the title compound.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08242145B2
Quelldatensatzuspto-grants-2012_08
ORD IDord-109d67210c824d2197eab30e47144060
Quellennotizuspto-grants-2012_08