4-Fluorobenzonitrile → (4-(2,6-Dimethylmorpholino)phenyl)methanamine

Reaktionsgleichung

F[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[CH:4][CH:3]=1.[CH3:10][CH:11]1[O:16][CH:15]([CH3:17])[CH2:14][NH:13][CH2:12]1>>[CH3:17][CH:15]1[O:16][CH:11]([CH3:10])[CH2:12][N:13]([C:2]2[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=2)[CH2:14]1

Komponenten

Edukt 2

HCID 145174-Fluorobenzonitrile

HCID 1108622,6-Dimethylmorpholine

Produkt 1

HCID 10443467(4-(2,6-Dimethylmorpholino)phenyl)methanamine

Versuchsvorschrift

4-Fluorobenzonitrile and 2,6-dimethylmorpholine were processed as described in Examples 66A and 66B to provide the title compound.

Quellen und Nachweise

ORD-Eintrag: ord-ade9e4ec21f84f549f4c38203919ec74
Quelldatensatz: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08247413B2

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