Nitric Acid → 2(3H)-Benzothiazolone, 6-nitro-

HRID 896505

Reaktionsgleichung

Reaktionsgleichung von HRID 896505
[S:1]1(=O)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[N+:11]([O-])([OH:13])=[O:12].C(OC(=O)C)(=[O:17])C>>[N+:11]([C:7]1[CH:8]=[CH:9][C:4]2[NH:3][C:2](=[O:17])[S:1][C:5]=2[CH:6]=1)([O-:13])=[O:12]

Komponenten

4

Edukt 3

HCID 944Nitric AcidHCID 7918Acetic AnhydrideHCID 53400715Benzothiazolinone

Produkt 1

HCID 6415712(3H)-Benzothiazolone, 6-nitro-

Reaktionsbedingungen

Temperatur
-10 °C

Versuchsvorschrift

0.1 mol of benzothiazolinone is dissolved in 100 ml of acetic anhydride and the solution is cooled to −10° C. 10 ml of nitric acid are then added dropwise, and the reaction is stirred for 2 hours. The resulting precipitate is filtered off and washed with water, and then purified by chromatography (eluant CH2Cl2 then AcOEt) to yield the title product, which is recrystallised from ethanol.

Aufarbeitung

  1. filtrationThe resulting precipitate is filtered off
  2. washwashed with water
  3. custompurified by chromatography (eluant CH2Cl2

Quellen und Nachweise

ORD-Eintrag
ord-1fbddb1298af4da6a2867526236a7614
Quelldatensatz
uspto-grants-2005_07
Patentnummer
US06919362B2

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