HCID 14203475, Verbindung → 2-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

HRID 905178Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 905178
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:6][CH:5]=1)([O-])=O>C(OCC)(=O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:10]2[O:11][CH2:12][C:13](=[O:16])[NH:14][N:15]=2)=[CH:8][CH:9]=1

Komponenten

4

Edukt 1

HCID 14203475HCID 14203475, Verbindung

Produkt 1

HCID 147428442-(4-aminophenyl)-5,6-dihydro-4H-1,3,4-oxadiazin-5-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

A solution of 2-p-nitrophenyl-4H,6H-1,3,4-oxadiazin-5-one (Example 17; 2.2 g.) in ethyl acetate (250 ml.) was hydrogenated in the prsence of a 5% palladium-on-charcoal catalyst at laboratory temperature and atmospheric pressure until 670 ml. of hydrogen had been absorbed. The mixture was filtered and the filtrate was evaporated to dryness. There was thus obtained as solid residue 2-p-aminophenyl-4H,6H-1,3,4-oxadiazin-5-one, m.p. 253°-255° C. (with decomposition).

Aufarbeitung

  1. customof hydrogen had been absorbed
  2. filtrationThe mixture was filtered
  3. customthe filtrate was evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-f58116059e5940ad8278e134a5d95d66
Quelldatensatz
uspto-grants-1983_12
Patentnummer
US04423045

Notizen zur Reaktion

Wird geladen…