Dimethylamine → [(3,4-Dimethoxy-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9056

Reaktionsgleichung

[CH3:1][C:2]1[NH:3][C:4]2[C:9]([CH:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[Cl-].[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][C:23]=1[O:24][CH3:25])[CH:17]=[N+:18]([CH3:20])[CH3:19].COC1C=C(C=CC=1OC)C=O.CNC>>[CH3:12][O:13][C:14]1[CH:15]=[C:16]([CH:17]([N:18]([CH3:20])[CH3:19])[C:10]2[C:9]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[NH:3][C:2]=2[CH3:1])[CH:21]=[CH:22][C:23]=1[O:24][CH3:25]

Komponenten

Edukt 4

HCID 674Dimethylamine

HCID 72242-Methylindole

HCID 8419Veratraldehyde

HCID 21985355(3,4-Dimethoxy-benzylidene)-dimethylammonium chloride

Produkt 1

HCID 21985318[(3,4-Dimethoxy-phenyl)-(2-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

Versuchsvorschrift

The preparation was carried out in accordance with general synthesis instructions 4 from 2-methyl-1H-indole and (3,4-dimethoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3,4-dimethoxy-benzaldehyde and dimethylamine.

Quellen und Nachweise

ORD-Eintrag: ord-df37569297e741cf9e39494a4a08895e
Quelldatensatz: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07091220B2

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