HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(R)-sec-butylamine → 4-(aminocarbonyl)-2-(ethylamino)-5-{[(1R)-1-methylpropyl]amino}benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (R)-sec-butylamine | HCID 2724537 | — |
| Edukt | ethyl 2-bromo-4-cyano-5-{[(1R)-1-methylpropyl]amino}benzoate | HCID 67404527 | — |
| Edukt | ethyl 4-cyano-2-(ethylamino)-5-{[(1R)-1-methylpropyl]amino}benzoate | HCID 67405722 | — |
| Produkt | 4-(aminocarbonyl)-2-(ethylamino)-5-{[(1R)-1-methylpropyl]amino}benzoic acid | HCID 57748590 | — |
Reaktionsschritte
Synthesized according to the method of reagent preparation 50 by using (1R)-1-methylpropylamine in step 1 then following step 2 with the conversion of ethyl 2-bromo-4-cyano-5-{[(1R)-1-methylpropyl]amino}benzoate to ethyl 4-cyano-2-(ethylamino)-5-{[(1R)-1-methylpropyl]amino}benzoate according to the method described in step 1 then proceeding through steps 3 and 4. MS (EI) for C14H21N3O3: 280 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08012956B2 |
| Quelldatensatz | uspto-grants-2011_09 |
| ORD ID | ord-445f68c7ef214569aad75372bc727aca |
| Quellennotiz | uspto-grants-2011_09 |