3,5-Dimethylpiperidine → 3,5-Dimethyl-4-(4-nitronaphthalen-1-yl)piperidine

Beteiligte Stoffe

Reaktionsschritte

A Pyrex tube was charged with 1-chloro-4-nitronaphthalene (52 mg, 0.25 mmol) and 3,5-dimethylpiperidine (133 μL, 1.0 mmol) followed by acetonitrile (2 mL). The tube was capped and the reaction tube was exposed to microwave irradiation (180° C., 5 min). The reaction mixture was filtered and the solid washed with cold ethanol. If needed the compound was purified according to Purification method C. Yield: 58 mg (82%).

Herkunft & Nachweise