Diethyl Ether → N-amino-2-(1-butynyl)-4-methoxypyridinium mesitylenesulfonate

HRID 9187

Reaktionsgleichung

Reaktionsgleichung von HRID 9187
[C:1]([C:5]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][N:6]=1)#[C:2][CH2:3][CH3:4].[C:13]1([CH3:26])[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[C:14]=1[S:21]([O:24][NH2:25])(=[O:23])=[O:22].C(OCC)C>ClCCl>[C:13]1([CH3:26])[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([CH3:20])[C:14]=1[S:21]([O-:24])(=[O:23])=[O:22].[NH2:25][N+:6]1[CH:7]=[CH:8][C:9]([O:11][CH3:12])=[CH:10][C:5]=1[C:1]#[C:2][CH2:3][CH3:4]

Komponenten

5

Edukt 3

HCID 3283Diethyl EtherHCID 11830845O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamineHCID 219846612-(1-Butynyl)-4-methoxypyridine

Produkt 1

HCID 21984631N-amino-2-(1-butynyl)-4-methoxypyridinium mesitylenesulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel2×

Versuchsvorschrift

To a solution of the obtained 2-(1-butynyl)-4-methoxypyridine (10.0 g) in dichloromethane (100 mL) there was added dropwise a solution of O-mesitylenesulfonylhydroxyamine (16.0 g) in dichloromethane (100 mL) at 0° C., and the mixture was stirred for 1 hour. Diethyl ether (250 mL) was added to the reaction mixture, and the precipitated solid was suction filtered and dried to obtain N-amino-2-(1-butynyl)-4-methoxypyridinium mesitylenesulfonate as a white salt (20.7 g).

Aufarbeitung

  1. filtrationfiltered
  2. customdried

Quellen und Nachweise

ORD-Eintrag
ord-0fbfc8c11b524a2cb943421f7379b2a2
Quelldatensatz
uspto-grants-2006_08
Patentnummer
US07091215B2

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