Water → 2-Chloro-9-cyclobutyl-7,7-difluoro-5-methyl-5,7,8,9-tetrahydro-pyrimido[4,5-b][1,4]diazepin-6-one

HRID 955212

Reaktionsgleichung

[C:25](=[O:26])([O-:27])[O-:28].[CH3:20][N:21]([CH3:22])[CH:23]=[O:24].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:19]1)[N:7]([CH:15]1[CH2:16][CH2:17][CH2:18]1)[CH2:8][C:9]([F:13])([F:14])[C:10](=[O:12])[NH:11]2.[Cs+:29].[Cs+:30].[I:31][CH3:32].[OH2:33]>>[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:19]1)[N:7]([CH:15]1[CH2:16][CH2:17][CH2:18]1)[CH2:8][C:9]([F:13])([F:14])[C:10](=[O:12])[N:11]2[CH3:20]