Diethyl Ether → 2H-Indeno[2,1-d]oxazol-2-one, 3,3a,4,8b-tetrahydro-, cis-
Reaktionsgleichung
Cl[C@@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][C@H:3]1[NH:11][C:12]([O:14]C(C)(C)C)=[O:13].C(OCC)C>C(Cl)(Cl)Cl>[O:13]1[C@H:2]2[C:10]3[C:5]([CH2:4][C@H:3]2[NH:11][C:12]1=[O:14])=[CH:6][CH:7]=[CH:8][CH:9]=3Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A solution of (±) trans-1-chloro-2-tert-butoxycarbonylaminoindane (10.0 g, 0.037 mol) in chloroform (200 ml) was heated under reflux in an argon atmosphere for 23 h. The mixture was concentrated in vacuo to give a brown solid. Trituration with diethyl ether afforded the title compound as a beige solid (6.0 g, 92%) m.p. 205°-206° C. which was used without further purification.
Aufarbeitung
- temperatureunder reflux in an argon atmosphere for 23 h
- concentrationThe mixture was concentrated in vacuo
- customto give a brown solid
Quellen und Nachweise
- ORD-Eintrag
- ord-5b8611b88a6e4c3d9cd3615833de6fae
- Quelldatensatz
- uspto-grants-1998_06
- Patentnummer
- US05773463
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