Ethyl alpha-benzylacetoacetate → HCID 178433370, Verbindung

HRID 965680

Reaktionsgleichung

Reaktionsgleichung von HRID 965680
[CH2:1]([CH:8]([C:14](=O)[CH3:15])[C:9](OCC)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)(O)O.[NH2:21][C:22]([NH2:24])=[NH:23]>C(O)C>[NH2:24][C:22]1[N:23]=[C:9]([OH:10])[C:8]([CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:14]([CH3:15])[N:21]=1

Komponenten

4

Edukt 2

HCID 246929Ethyl alpha-benzylacetoacetateHCID 286947Carbonic acid-guanidine (1:1)

Produkt 1

HCID 178433370HCID 178433370, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of ethyl 2-benzyl-3-oxobutanoate (6 g, 27.2 mmol), guanidine carbonate (2.94 g, 16.3 mmol) and ethanol (20 ml) was refluxed for 10 hours. After cooling, the precipitate was filtered and washed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%).

Aufarbeitung

  1. temperaturewas refluxed for 10 hours
  2. temperatureAfter cooling
  3. filtrationthe precipitate was filtered
  4. washwashed with water, ethanol and ether in order, to the object compound (3.62 g, 61.7%)

Quellen und Nachweise

ORD-Eintrag
ord-f19885d0bc5e4cc6916e9d57a48c49c4
Quelldatensatz
uspto-grants-2005_10
Patentnummer
US06951866B2

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