Methanesulfonyl chloride → HCID 178484128, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([CH2:13][C@H:14]2[CH2:19][CH2:18][C@H:17]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][OH:25])[CH2:16][CH2:15]2)[CH3:12])(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH3:26][S:27](Cl)(=[O:29])=[O:28]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8]([N:11]([CH2:13][C@H:14]2[CH2:19][CH2:18][C@H:17]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][O:25][S:27]([CH3:26])(=[O:29])=[O:28])[CH2:16][CH2:15]2)[CH3:12])(=[O:9])=[O:10])=[CH:4][CH:3]=1Komponenten
3
Versuchsvorschrift
In analogy to the procedure described in example 3.4, trans-4-chloro-N-[4-(4-hydroxy-butoxy)-cyclohexylmethyl]-N-methyl-benzenesulfonamide was treated with methanesulfonyl chloride to yield trans-methanesulfonic acid 4-(4-{[(4-chloro-benzenesulfonyl)-methyl-amino]-methyl}-cyclohexyloxy)-butyl ester as colorless solid, MS: 468 (MH+, 1Cl).
Quellen und Nachweise
- ORD-Eintrag
- ord-1fdcc485293344e5b050818b60dca33c
- Quelldatensatz
- uspto-grants-2005_10