Sodium 4-methylbenzenesulfonate → 4-Methylphenylbenzylpiperidinium tosylate
Reaktionsgleichung
[Br-].[CH3:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]2([CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[C:22]1([CH3:32])[CH:27]=[CH:26][C:25]([S:28]([O-:31])(=[O:30])=[O:29])=[CH:24][CH:23]=1.[Na+]>O>[S:28]([C:25]1[CH:26]=[CH:27][C:22]([CH3:32])=[CH:23][CH:24]=1)([O-:31])(=[O:30])=[O:29].[CH3:2][C:3]1[CH:4]=[CH:5][C:6]([N+:9]2([CH2:15][C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)=[CH:7][CH:8]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
An aqueous solution prepared by dissolving 4-methylphenylbenzylpiperidinium bromide (13.85 g, 0.04 mmol) and sodium p-toluenesulfonate (9.32 g, 0.048 mmol) in 50 ml of deionized water was extracted with 50 ml of chloroform twice by using a separating funnel. The resulting chloroform phases were combined and the combined solution was washed with 50 ml of deionized water, followed by filtration and drying to obtain 4-methylphenylbenzylpiperidinium tosylate (16.1 g, yield: 92%).