HCID 19968441, Verbindung → HCID 10220867, Verbindung

HRID 975828Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 975828
S(O)(O)(=O)=O.[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:18]3([CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[NH:17][CH2:16][CH2:15][CH:14]=2)=[CH:9][CH:8]=1>O>[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:18]3([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[NH:17][CH2:16][CH2:15][CH:14]=2)=[CH:9][CH:8]=1

Komponenten

3

Edukt 1

HCID 19968441HCID 19968441, Verbindung

Produkt 1

HCID 10220867HCID 10220867, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel2×

Versuchsvorschrift

A mixture of 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene sulphate (0.5 g, prepared as described in Example 5) and water (5 ml) was stirred at ambient temperature to give, initially, a mobile suspension which rapidly thickened. Water (5 ml) was added to aid mobility and the solid was collected by filtration, washed with water (5 ml) and dried in vacuo at ambient temperature to give 5-(4-chlorophenyl)-1-azaspiro[5.5]undec-4-ene 0.5 sulphate, 2.1 hydrate as a white solid. Yield 0.3 g, mp 205°-215° C.

Aufarbeitung

  1. customto give
  2. filtrationthe solid was collected by filtration
  3. washwashed with water (5 ml)
  4. customdried in vacuo at ambient temperature

Quellen und Nachweise

ORD-Eintrag
ord-a5d880275bbe46b8bbafc0240e40e2b8
Quelldatensatz
uspto-grants-1997_03
Patentnummer
US05610161

Notizen zur Reaktion

Wird geladen…