Nitric Acid → 2-(3-Methyl-4-nitrophenyl)benzonitrile

HRID 976588

Reaktionsgleichung

Reaktionsgleichung von HRID 976588
[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=2[C:10]#[N:11])[CH:5]=[CH:6][CH:7]=1.[N+:16]([O-])([OH:18])=[O:17].S(=O)(=O)(O)O>O>[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=2[C:10]#[N:11])[CH:5]=[CH:6][C:7]=1[N+:16]([O-:18])=[O:17]

Komponenten

5

Edukt 3

HCID 944Nitric AcidHCID 1118Sulfuric AcidHCID 13942432-(3-Methylphenyl)benzonitrile

Produkt 1

HCID 214689052-(3-Methyl-4-nitrophenyl)benzonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

2-(3-Methylphenyl)benzonitrile (18.1 moles, 3.5 g) was added slowly at -5° C. to a mixture of 10 ml nitric acid and 10 ml sulfuric acid. After 5 minutes, the reaction was diluted with cold water. The solid was collected, dissolved in THP. The solution was dried and concentrated. The solid was recrystallized from ether and hexane to yield 2.45 g of 2-(3-methyl-4-nitrophenyl)benzonitrile. (MS)

Aufarbeitung

  1. customThe solid was collected
  2. dissolutiondissolved in THP
  3. customThe solution was dried
  4. concentrationconcentrated
  5. customThe solid was recrystallized from ether and hexane

Quellen und Nachweise

ORD-Eintrag
ord-03628136d8bf4f05a010552e7b9d6628
Quelldatensatz
uspto-grants-1997_03
Patentnummer
US05612360

Verknüpfte Notizen

Wird geladen…