Piperidine → 4-[(3,4-Dihydroxy-5-cyanophenyl)methylidene]-2-thioxoimidazolidin-5-one

HRID 977205

Reaktionsgleichung

[NH:1]1[CH2:7][C:5](=[O:6])[NH:4][C:2]1=[S:3].[OH:8][C:9]1[CH:10]=[C:11]([CH:14]=[C:15]([C:18]#[N:19])[C:16]=1[OH:17])[CH:12]=O.N1CCCCC1>C(O)(=O)C>[OH:8][C:9]1[CH:10]=[C:11]([CH:12]=[C:7]2[C:5](=[O:6])[NH:4][C:2](=[S:3])[NH:1]2)[CH:14]=[C:15]([C:18]#[N:19])[C:16]=1[OH:17]

Komponenten

Reaktionsbedingungen

Temperatur: 100 °C

Versuchsvorschrift

A solution containing 0.58 g of thiohydantoin, 0.82 g of 3,4-dihydroxy-5-cyanobenzaldehyde and 0.1 ml of piperidine in 10 ml of acetic acid was heated for 4 h at 100° C. The product was filtered and washed with ether. Yield 0.51 g, mp 210°-213° C.

Aufarbeitung

filtrationThe product was filtered
washwashed with ether

Quellen und Nachweise

ORD-Eintrag: ord-9a48546ee4fd456493cbf86ab7ca7bd5
Quelldatensatz: uspto-grants-1997_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05614541

Verknüpfte Notizen

Wird geladen…